早在19世纪人们经过研究发现，细胞癌变过程中，细胞核会发生明显的改变。随着遗传学和分子遗传学的更深入的研究表时；染色体易位、基因缺失、扩增 及重排是白血病发生的主要因素，同时还发现不同位点的基因改变引起对应不同类型的白血病类型。使用FISH技术能够检测出这些发生改变的基因，从而诊断出对应类型的白血病。Cytocell提供一系列使用简单、快速的液体和特有的固体探针，方便客户使用。
|
探针名称 |
标记位点 |
染色体区域 |
质控探针 |
人份 |
货号 |
| 13q14.3Probe |
13q14.3 |
Deletion |
13qter |
10 |
LPH006 |
| Apha satellite 12 red for CLL |
|
|
N/A |
10 |
LPH028 |
| AML1/ETO Dual Fusion |
21q22/8q21.3 |
Translocation |
N/A |
10 |
LPH026 |
| AML1 |
21q22 |
Breakapart |
N/A |
10 |
LPH027 |
| ATM Probe |
11q22 |
Deletion |
D11Z1 |
10 |
LPH011 |
| BCL 6 |
3q27.3 |
Breakapart |
N/A |
10 |
LPH35 |
| BCR/ABL Plus Dual Fusion |
9q34/22q10 |
Translocation/Deletion |
N/A |
10 |
LPH38 |
| BCR/ABL Dual Fusion |
9q34/22q11 |
Trans/ocation |
N/A |
10 |
LPH007 |
| CBFβ/MYH11 Dual Fusion |
16q22/16p13 |
Trans/ocation |
N/A |
10 |
LPH022 |
| CKS1B/CDKN2C(P18) |
1q21/1p32.3 |
Amplification/Deletion |
N/A |
10 |
LPH039 |
| CMYC |
8q24 |
Breakapart |
N/A |
10 |
LPH010 |
| D13S25 |
13q14.3 |
Deletion |
D13S1826 |
10 |
LPH043 |
| D13S319 |
13q14.3 |
Deletion |
D13S1826 |
10 |
LPH042 |
| Del(5q)Probe |
5q31 |
Deletion |
5p15.31 |
10 |
LPH024 |
| Del(7q)Probe |
7q22.1/7q31 |
Deletion |
N/A |
10 |
LPH025 |
| Del(20q)Probe |
20q12/20q13.2 |
Deletion |
N/A |
10 |
LPH020 |
| E2A Probe |
19p13 |
Breakapart |
N/A |
10 |
LPH019 |
| EVI1 Probe |
3q26 |
Breakapart |
N/A |
10 |
LPH036 |
| FIP1L1/CHIC2/PDGFRA |
4q12 |
Translocation |
N/A |
10 |
LPH032 |
| IGH Probe |
14q32 |
Breakapart |
N/A |
10 |
LPH014 |
| IGH/BCL2 Dual Fusion |
14q32/18q21 |
Translocation |
N/A |
10 |
LPH018 |
| IGH/CCND1(BCL1)Dual Fusion |
14q32.3/11q13 |
Translocation |
N/A |
10 |
LPH021 |
| IGH/CCND3 Dual Fusion |
14q32.3/6q21 |
Translocation |
N/A |
10 |
LPH040 |
| IGH/CMYC Dual Fusion |
14q32.3/8q24.21 |
Translocation |
N/A |
10 |
LPH041 |
| IGH/FGFR3 Dual Fusion |
14q32.3/4p16.3 |
Translocation |
N/A |
10 |
LPH030 |
| IGH/MAF Dual Fusion |
14q32.3/16q22 |
Translocation |
N/A |
10 |
LPH029 |
| IGH/MAFB Dual Fusion |
14q32.3/20q11 |
Translocation |
N/A |
10 |
LPH044 |
| IGH/MYEOV Dual Fusion |
14q32.3/20q12 |
Translocation |
N/A |
10 |
LPH045 |
| IGK Probe |
2p12 |
Breakapart |
N/A |
10 |
LPH034 |
| IGK Probe |
22q12 |
Breakapart |
N/A |
10 |
LPH033 |
| MLL Probe |
11q23 |
Breakapart |
N/A |
10 |
LPH013 |
| MYB Probe |
6q23 |
Deletion |
D6Z1 |
10 |
LPH016 |
| P16Probe |
9p21 |
Deletion |
D9Z3 |
10 |
LPH009 |
| P53Probe |
17p13 |
Deletion |
N/A |
10 |
LPH017 |
| PFGFRB |
5q32 |
Breakapart |
N/A |
10 |
LPH031 |
| PML/RARαDusl Fusion |
15q22/17q21 |
Translocation |
N/A |
10 |
LPH023 |
| TEL/AML1 Dual Fusion |
12p13.3/21q22 |
Translocation |
N/A |
10 |
LPH012 | |
| *for 5 test kit add-S to catalogue number.Eg:LPH###-S | |
