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商品详细描述
产品名称:紫杉醇拉 丁 名:Chinese yew提取部位:树皮提取方法:酒精&酸碱提取产品外观:白色或类白色粉末产品规格:99.5% CAS 号:33069-62-4抗癌类药品,紫杉醇属有丝分裂中的微管抑制剂,紫杉醇具有聚合和稳定细胞内微管的作用,致使快速分裂的肿瘤细胞在有丝分裂阶段被牢牢固定,使微管不再分开,可阻断细胞于细胞周期之G2与M期,使癌细胞复制受阻断而死亡 。 Production Name:Paclitaxel or TaxolOriginal plant:Chinese yewSpecification:99.5%Test Method:HPLCChemical Name:Benzenepropanoic acid,β-(benzoylamino)-α-hydroxy-, 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, [2aR-[2a,4β,4a,β6β,9(R*,βS*),11α,12α,12aα,12bα]]-. (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-Dodecahydro-4,6,9,11,12,12b-hexahydroxy-4a,8,13,13-tetramethyl-7,11-methano-5H-cyclodeca[3,4]-benz[1,2-b]oxet-5-one 6,12b-diacetate, 12-benzoate, 9-ester with (2R,3S)-N-benzoyl-3-phenylisoserineMolecular Formula:C47H51NO14Molecular Weight:853.91Appearance: White to off-white powderSolubility:Insoluble in water, soluble in alcohoCAS No:33069-62-4
Description:Paclitaxel-treated cells have defects in mitotic spindle assembly, chromosome segregation, and cell division. Unlike other tubulin targeted drugs such as colchicine that inhibit microtubule assembly, however, paclitaxel stabilizes the microtubule polymer and protects it from disassembly. The inability of the chromosomes to achieve a metaphase spindle configuration leads to a mitotic block in which there is prolonged activation of the mitotic checkpoint with the subsequent triggering of apoptosis or slippage back into the G1-phase of the cell cycle without cell division.The ability of paclitaxel to inhibit spindle function is generally attributed to its suppression of microtubule dynamics;but recent studies have demonstrated that suppression of dynamics occurs at concentrations lower than those needed to block mitosis. At the higher antimitotic concentrations, paclitaxel appears to act by suppressing microtubule detachment from centrosomes, a process normally activated during mitosis.The binding site for paclitaxel has been shown to reside on the beta-tubulin subunit.
01 Red Clover extract Isoflavones8-40%
02 Resveratrol 20-98%
03 Galanthamine HBr 99%
04 Limonin 98%
05 Gingko Biloba Extract CPh,USP,DAB,EP
06 Ginseng extract Ginsenosides 80%
07 Milk Thistle extract Silymarins80%
08 Epimdium extract Icariin 10%-98%
09 Lycopene 5%-90%
10 Griffonia Seed extract 5-HTP 98%
11 Horse Chestnut extract Aescin 20-98%
12 Zeaxanthin 5%-50%
13 Grape Seed extract Polyphenols85%,95%;OPC 95%,98%
14 Bilberry Extract Anthocyanidins 25%
15 Saw Palmetto extract Total fatty acids 25%,45%
16 Huperzine A 1%,5%,98%
17 Lutein 5-90%
18 Soybean extract Soy Isoflavones 20-40%
19 SOD 3000IU/mg
20 Schisandra extract Schisandrins 1-9%
21 Yohimbine Hydrochlori 98%
22 Stevia Extract Steviosides 80%-97%
23 Black Pepper extract 98%piperine
24 Tribulus Terrestris extract Tribuloside 40%-90%
25St
Johns Wort extract Hypericin
0.3%
26 Rhodiola extract Salidroside 1-10%,Rosavins3%
27 Ginger Extract Gingerols 5%
28 Reishi Mushroom Extract Polysaccharides 10-60%;triterpene 1-6%
29 Green Tea Extract Polyphenol 40-98%
30 Citrus Auratium Extract Synephrine 6-98%
31 Echinacea Extract Total phenol 4%;Cichoric acid 4%
32 Rosemary Extract Carnosic acid 5-90%;Rosmarinic acid 2.5-20%
33 WhiteWillow
Bark Extract Salicin 15%~50%
34 Wild Yaw Extract Diosgenine8-20%
35 Angelica Extract Ligustilide 1%
36 Kudzu Root Extract Isoflavones/ puerarin 40%
37 Chlorogenic acid 25-98%
38 Centella Asiatica extract Asiaticoside 10-90%
39 Wolfberry extract Polysaccharides20-50%
40 Astragalus extract Astragalosides0.3-20%,Polysaccharides 20-50%
41 Siberian Ginseng extract Eleutheroside B+E 0.8%
42 Shiitake Mushroom extract Polysaccharides10-30%
43 Hawthorn extract Flavnones 10-30%
44 Ellagic acids 40-95%
45 American Ginseng Extract Ginsenosides 5-80%
46 Herba Andrographis Extract Andrographolide 5-98%
47 Cordyceps extract Polysaccharides10-40%
48 Red Yeast Rice extract Lovastatin 0.4-3%
49 Agaricus blazei Murrill extract Polysaccharides 30%
50 Bitter Melon extract Charantin 10%
51 Valerian Root extract Valerianic acid 0.4%,0.8%
52 Passion flower extract Flavnones 4%
53 Ursolic acid 98%
54 Gynostemma extract Gypenosides 20-98%
55 Acetyl-resveratrol 98%
01 Red Clover extract Isoflavones8-40%
02 Resveratrol 20-98%
03 Galanthamine HBr 99%
04 Limonin 98%
05 Gingko Biloba Extract CPh,USP,DAB,EP
06 Ginseng extract Ginsenosides 80%
07 Milk Thistle extract Silymarins80%
08 Epimdium extract Icariin 10%-98%
09 Lycopene 5%-90%
10 Griffonia Seed extract 5-HTP 98%
11 Horse Chestnut extract Aescin 20-98%
12 Zeaxanthin 5%-50%
13 Grape Seed extract Polyphenols85%,95%;OPC 95%,98%
14 Bilberry Extract Anthocyanidins 25%
15 Saw Palmetto extract Total fatty acids 25%,45%
16 Huperzine A 1%,5%,98%
17 Lutein 5-90%
18 Soybean extract Soy Isoflavones 20-40%
19 SOD 3000IU/mg
20 Schisandra extract Schisandrins 1-9%
21 Yohimbine Hydrochlori 98%
22 Stevia Extract Steviosides 80%-97%
23 Black Pepper extract 98%piperine
24 Tribulus Terrestris extract Tribuloside 40%-90%
25
26 Rhodiola extract Salidroside 1-10%,Rosavins3%
27 Ginger Extract Gingerols 5%
28 Reishi Mushroom Extract Polysaccharides 10-60%;triterpene 1-6%
29 Green Tea Extract Polyphenol 40-98%
30 Citrus Auratium Extract Synephrine 6-98%
31 Echinacea Extract Total phenol 4%;Cichoric acid 4%
32 Rosemary Extract Carnosic acid 5-90%;Rosmarinic acid 2.5-20%
33 White
34 Wild Yaw Extract Diosgenine8-20%
35 Angelica Extract Ligustilide 1%
36 Kudzu Root Extract Isoflavones/ puerarin 40%
37 Chlorogenic acid 25-98%
38 Centella Asiatica extract Asiaticoside 10-90%
39 Wolfberry extract Polysaccharides20-50%
40 Astragalus extract Astragalosides0.3-20%,Polysaccharides 20-50%
41 Siberian Ginseng extract Eleutheroside B+E 0.8%
42 Shiitake Mushroom extract Polysaccharides10-30%
43 Hawthorn extract Flavnones 10-30%
44 Ellagic acids 40-95%
45 American Ginseng Extract Ginsenosides 5-80%
46 Herba Andrographis Extract Andrographolide 5-98%
47 Cordyceps extract Polysaccharides10-40%
48 Red Yeast Rice extract Lovastatin 0.4-3%
49 Agaricus blazei Murrill extract Polysaccharides 30%
50 Bitter Melon extract Charantin 10%
51 Valerian Root extract Valerianic acid 0.4%,0.8%
52 Passion flower extract Flavnones 4%
53 Ursolic acid 98%
54 Gynostemma extract Gypenosides 20-98%
55 Acetyl-resveratrol 98%
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